Holladay, Carolyn

Research Interests

Tendon repair
Tendon stem cells
Cell-based therapy

Professional Qualifications

PhD in Tissue Engineering, National University of Ireland, Galway, Ireland
B.A.Sc. Chemical Engineering (Biomedical Speciality) 2007, University of Toronto, Canada

Publications

C. Holladay, A. Duffy, X. Chen, T. O’Brien, M. Sefton, A. Pandit. Recovery of cardiac function mediated by MSC and interleukin-10 plasmid functionalised scaffold. Biomaterials. (In Publication, accepted 10/10/2011)
C. Holladay, M. Kulkarni, W. Minor, A. Pandit. “Gene Therapy” in: The Biomedical Engineering Handbook (4th Ed.). Edited by: JD Bronzino & DR. Peterson: CRC Press. (In publication)
K. Fitzgerald, C. Holladay, C. McCarthy, K. Power, A. Pandit, W. Gallagher. Standardization of models and methods used to assess nanoparticles in cardiovascular applications. Small 2011, 7 (6), 705-717.
C. Holladay, K. Power, M. Sefton, T. O’Brien, W. Gallagher, A. Pandit. Functionalized scaffold mediated interleukin-10 gene delivery significantly improves survival rates of stem cells in vivo. Molecular Therapy, 2011;19(5):969-78.
C. Holladay, M. Keeney, B. Newland, A. Mathew, W. Wang, A. Pandit. A reliable method for detecting complexed DNA in vitro. Nanoscale, 2010, 2(12), 2718-23.
C. Holladay, T. O'Brien, A. Pandit. Non-viral gene therapy for myocardial engineering. Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology, 2009; 2: 232-48.
R. Vinas-Castells, C. Holladay, A. di Luca, V.M. Diaz, A. Pandit. Snail1 Down-Regulation using Small Interfering RNA Complexes Delivered through Collagen Scaffolds. Bioconjugate Chemistry, 2009; 20: 2262-9.
C. Holladay, M. Keeney, U. Greiser, M. Murphy, T. O'Brien, A. Pandit. A matrix reservoir for improved control of non-viral gene delivery. Journal of Controlled Release 2009; 136: 220-5